Frontier Neuroscience Research

Decoding the Human Brain One Synapse at a Time

We are a multidisciplinary research institute pushing the boundaries of neuroscience — from molecular circuits to cognitive behavior and neurological disease.

240+
Published Papers
48+
Researchers
12+
Active Studies
Prefrontal Temporal Limbic
Live fMRI Study
Neural activity
847 Hz ↑ 12%
Latest Discoveries

Research Highlights

Groundbreaking findings from our labs, shaping the future of neuroscience and medicine.

Connectivity Mar 2025

Mapping Default Mode Network Disruptions in Early Alzheimer's

Using high-resolution fMRI, we identified novel biomarkers of DMN disruption appearing up to 8 years before clinical diagnosis.

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Molecular Feb 2025

CRISPR-Mediated Correction of SCN1A Mutations in Dravet Syndrome

Proof-of-concept gene editing in patient-derived iPSC neurons shows 94% reduction in aberrant sodium channel activity.

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BCI Jan 2025

High-Bandwidth Neural Interface Achieves 1,024-Channel Cortical Recording

Our next-gen flexible electrode array sets a new record for simultaneous cortical unit recording with sub-millisecond latency.

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Plasticity Dec 2024

Theta-Burst Stimulation Enhances Long-Term Potentiation in Hippocampal CA1

Non-invasive TMS protocol demonstrates 3x improvement in synaptic strength, with implications for memory rehabilitation.

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Perception Nov 2024

Visual Cortex Predictive Coding During Ambiguous Perception Tasks

EEG-decoded neural signatures reveal a 40ms predictive window preceding conscious perception, refining Bayesian brain models.

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Pharmacology Oct 2024

Selective mGluR5 Antagonism Reduces Anxiety Circuits Without Sedation

Novel compound NL-7712 targets amygdala-prefrontal circuits with high specificity, showing promise in treatment-resistant anxiety.

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Disciplines

Research Areas

Six interconnected disciplines, one unified mission: understanding the brain.

Cognitive Neuroscience

We investigate the neural substrates of higher cognitive functions — memory, attention, decision-making, and language — using a combination of neuroimaging, psychophysics, and computational modeling.

Working Memory
Prefrontal-parietal network dynamics during WM encoding and retrieval
Decision Making
Orbitofrontal and striatal contributions to value-based choice
Attention Systems
Top-down vs bottom-up attentional control mechanisms
Language Networks
Broca-Wernicke connectivity and semantic processing
18 active projects 64 publications $4.2M funding
Key Methods
7T fMRI Neuroimaging
256-ch High-density EEG
Eye-tracking + Pupillometry
Drift-Diffusion Modeling
TMS / tDCS Stimulation
MVPA Decoding
Peer-Reviewed

Latest Publications

Nature Neuroscience 2025 · IF 25.1

Whole-brain connectome alterations precede symptom onset in prodromal Parkinson's disease

Chen L., Nakamura R., Osei K., et al. — NeuroLab Connectivity Group

142
Citations
Science 2025 · IF 56.9

Single-cell transcriptomics reveals novel interneuron subtypes in human prefrontal cortex

Volkov A., Martinez S., Kim J., et al. — Molecular Circuits Lab

98
Citations
Cell 2024 · IF 66.8

Astrocyte calcium signaling gates hippocampal memory consolidation during NREM sleep

Petrov I., Hassan N., Tran M., et al. — Glial Biology Unit

211
Citations
Nature Methods 2024 · IF 48.0

DeepNeuro: A foundation model for multi-modal neural data analysis and decoding

Zhao W., Fernandez C., Osei K., et al. — Computational Neuroscience Lab

334
Citations
The People

Our Research Team

World-class scientists united by curiosity and a commitment to advancing human health.

Dr. Sarah Chen

Dr. Sarah Chen

Director · Cognitive Neuroscience

PhD MIT. Pioneering work on predictive coding and working memory circuits.

Dr. Alexei Volkov

Dr. Alexei Volkov

PI · Molecular Circuits Lab

PhD Karolinska. Expert in single-cell genomics and interneuron diversity.

Dr. Nadia Hassan

Dr. Nadia Hassan

PI · Glial Biology Unit

PhD Oxford. Focuses on astrocyte-neuron interactions and sleep memory consolidation.

Dr. Wei Zhao

Dr. Wei Zhao

PI · Computational Neuro Lab

PhD Stanford. Creator of DeepNeuro, a foundation model for neural data analysis.

240+
Peer-Reviewed Papers
$28M
Research Funding
48+
Scientists & Staff
12+
Active Clinical Trials
Get Involved

Join the Frontier of
Brain Science

Whether you're a researcher, clinician, or institution — we welcome collaborations, postdoc applications, and partnership inquiries.

Postdoc Program

Open positions across all six research divisions. Rolling applications accepted.

Industry Partnerships

Collaborate with our labs on translational research and licensing opportunities.

Stay Updated

Get our monthly research digest — new papers, open positions, and events.

Send Us a Message

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